Martin Braddock Selected Research

fostamatinib

1/2018	Translational Biomarkers and Ex Vivo Models of Joint Tissues as a Tool for Drug Development in Rheumatoid Arthritis.
3/2016	Atheroprotection through SYK inhibition fails in established disease when local macrophage proliferation dominates lesion progression.
10/2015	Prevention of fostamatinib-induced blood pressure elevation by antihypertensive agents.
1/2015	The active metabolite of spleen tyrosine kinase inhibitor fostamatinib abrogates the CD4⁺ T cell-priming capacity of dendritic cells.

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Martin Braddock Research Topics

Disease

9	Inflammation (Inflammations) 01/2018 - 04/2003
6	Rheumatoid Arthritis 01/2018 - 06/2004
6	Non-alcoholic Fatty Liver Disease 12/2016 - 02/2015
5	Neoplasms (Cancer) 01/2018 - 09/2013
4	Asthma (Bronchial Asthma) 01/2019 - 01/2018
4	Hepatocellular Carcinoma (Hepatoma) 09/2016 - 01/2015
4	Liver Diseases (Liver Disease) 05/2015 - 07/2014
3	Infections 01/2018 - 07/2006
3	Arthritis (Polyarthritis) 11/2014 - 04/2005
3	Immune System Diseases (Immune Disorders) 06/2007 - 05/2004
2	Colorectal Neoplasms (Colorectal Cancer) 05/2016 - 01/2015
2	Atherosclerosis 03/2016 - 09/2005
2	Insulin Resistance 01/2016 - 11/2014
2	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 09/2015 - 03/2015
2	End Stage Liver Disease 08/2015 - 01/2015
1	Hypersensitivity (Allergy) 01/2019
1	Anaphylaxis (Anaphylactic Shock) 01/2019
1	Airway Remodeling 01/2018
1	Atopic Dermatitis (Atopic Eczema) 01/2018
1	Disease Progression 01/2018
1	Hepatorenal Syndrome 11/2017
1	Hypercholesterolemia 03/2016
1	Dyslipidemias (Dyslipidemia) 02/2016
1	Thrombosis (Thrombus) 02/2016
1	Kidney Diseases (Kidney Disease) 02/2016
1	Hyperthyroidism 01/2016
1	Hepatitis 01/2016
1	Obstructive Jaundice (Cholestatic Jaundice) 01/2016
1	Critical Illness (Critically Ill) 01/2016
1	Hypoglycemia (Reactive Hypoglycemia) 01/2016
1	Hyperuricemia 01/2016
1	Gout 01/2016
1	Hyperglycemia 01/2016
1	Crohn Disease (Crohn's Disease) 10/2015
1	Abdominal Pain (Pain, Abdominal) 10/2015
1	Sclerosing Cholangitis 09/2015
1	Liver Neoplasms (Liver Cancer) 01/2015
1	Neoplasm Metastasis (Metastasis) 01/2015

Drug/Important Bio-Agent (IBA)

9	Pharmaceutical PreparationsIBA 01/2019 - 04/2003
6	CytokinesIBA 01/2019 - 06/2004
5	Biomarkers (Surrogate Marker)IBA 01/2018 - 11/2014
5	Biological ProductsIBA 01/2018 - 06/2004
4	fostamatinibIBA 01/2018 - 01/2015
4	Uric Acid (Urate)IBA 01/2016 - 02/2015
3	tralokinumabIBA 01/2019 - 01/2018
2	Monoclonal AntibodiesIBA 01/2019 - 01/2018
2	Interleukin-13IBA 01/2018 - 01/2018
2	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2018 - 03/2015
2	LDL CholesterolIBA 12/2016 - 02/2016
2	ORALIT (ORS)IBA 12/2016 - 05/2015
2	oxidized low density lipoproteinIBA 12/2016 - 02/2016
2	Carcinoembryonic AntigenIBA 05/2016 - 02/2015
2	Therapeutic UsesIBA 01/2016 - 11/2014
2	Ursodeoxycholic Acid (Urso)FDA LinkGeneric 09/2015 - 03/2015
2	InterferonsIBA 07/2015 - 07/2014
2	Hormones (Hormone)IBA 05/2015 - 11/2014
2	Methotrexate (Mexate)FDA LinkGeneric 03/2015 - 11/2010
2	Purinergic P2X7 ReceptorsIBA 11/2014 - 10/2007
2	Interleukin-18 (Interleukin 18)IBA 10/2007 - 06/2004
1	AntibodiesIBA 01/2019
1	InterleukinsIBA 01/2019
1	collagen type I trimeric cross-linked peptideIBA 01/2018
1	CollagenIBA 01/2018
1	Collagen Type I (Type I Collagen)IBA 01/2018
1	Matrix Metalloproteinases (MMPs)IBA 01/2018
1	Immunoglobulin E (IgE)IBA 01/2018
1	Antirheumatic Agents (DMARD)IBA 01/2018
1	Interleukin-4 (Interleukin 4)IBA 01/2018
1	Vasoconstrictor AgentsIBA 11/2017
1	Toll-Like Receptors (Toll-Like Receptor)IBA 09/2016
1	Pattern Recognition ReceptorsIBA 09/2016
1	C-Reactive ProteinIBA 03/2016
1	CholesterolIBA 03/2016
1	Apolipoproteins E (ApoE)IBA 03/2016
1	Cytidine Triphosphate (CTP)IBA 02/2016
1	Methimazole (Thiamazole)FDA LinkGeneric 01/2016
1	InflammasomesIBA 01/2016
1	Glucose (Dextrose)FDA LinkGeneric 01/2016
1	Hypoglycemic Agents (Hypoglycemics)IBA 01/2016
1	Blood Glucose (Blood Sugar)IBA 01/2016
1	Syk KinaseIBA 10/2015
1	Tyrosine Kinase InhibitorsIBA 10/2015
1	AZD9056IBA 10/2015
1	Purinergic Receptors (Receptors, Purine)IBA 10/2015
1	Metronidazole (Metric)FDA LinkGeneric 09/2015
1	Mycophenolic Acid (Cellcept)FDA LinkGeneric 09/2015
1	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 05/2015
1	Colchicine FDA LinkGeneric 03/2015
1	BezafibrateIBA 03/2015
1	HDL LipoproteinsIBA 02/2015
1	Triglycerides (Triacylglycerol)IBA 02/2015
1	Fetal Proteins (Fetoprotein)IBA 01/2015

Therapy/Procedure

11	Therapeutics 11/2017 - 04/2005
3	Drug Therapy (Chemotherapy) 07/2015 - 09/2013
1	Aftercare (After-Treatment) 01/2016
1	Homologous Transplantation 08/2015
1	Immunotherapy 07/2015
1	Radiotherapy 07/2015
1	Adjuvant Chemotherapy 01/2015
1	Surgical Instruments (Clip) 01/2015